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Acetylsalicylic acid-Darnitsa

Analgesics and antipyretics

Acetylsalicylic acid is nonsteroidal anti-inflammatory drug, a salicylate derivative. The chief mechanism of action of acetylsalicylic acid is inactivation of the COX (cyclooxygenase) resulting in decreased production of inflammatory mediators: prostaglandins, prostacyclins, and thromboxane.

For symptomatic treatment of headache, toothache; sore throat; dysmenorrhea; muscle and joint pain; backache; moderate pain due to arthritis.

In colds or acute respiratory infections for symptomatic relief of pain and fever.

Acetylsalicylic acid-Darnitsa is taken after meals with an adequate amount of water.

Acetylsalicylic acid-Darnitsa should not be taken for longer than 3–5 days without your physician's advice.

Adults and children over 15 years.

500–1,000 mg as a single dose. Next use is possible after 4–8 hours. The maximum daily dose should not exceed 4 g.

Warnings and precautions.

In patients with concomitant liver or renal dysfunction, it is necessary to lower the dose or increase the interval between doses.


The drug is intended for children aged 15 years and over.

Acetylsalicylic acid-containing drugs should not be used in children with acute respiratory viral infection with or without a fever. In some viral diseases, especially in influenza A and B and in chickenpox, there is a risk of Reye syndrome development. Reye syndrome is a very rare but life-threatening disease and requires immediate medical attention. The risk may be higher when acetylsalicylic acid is used as an adjuvant; however, the causal effect has not been proven in this case. If the above conditions are accompanied by prolonged vomiting, this may be a sign of Reye syndrome.

Specialized edition for medical institutions and doctors.