Nonsteroidal anti-inflammatory and anti-rheumatic drugs. Propionic acid derivatives. Dexketoprofen
Dexketoprofen trometamol is a propionic acid salt that has analgesic, anti-inflammatory and antipyretic properties and belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). Its mechanism of action is based on the reduction of prostaglandin synthesis by inhibiting cyclooxygenase.
Symptomatic treatment of moderate to intense acute pain when oral medication is impractical, e.g. postoperative pain, renal colic, and lower back pain (back pain).
The recommended dose for adults is 50 mg every 8–12 hours. If necessary, readminister the dose after 6 hours. The maximum daily dose should not exceed 150 mg. The medicine is for short-term use only, hence it should only be used during periods of acute pain (for no longer than 2 days). Patients should be switched to oral analgesics when possible. Adverse reactions can be reduced by administering the lowest effective dose within the shortest time necessary to improve the condition. In moderate or severe postoperative pain, the medicine may be used as indicated in the same recommended doses in combination with opioid analgesics.