Muscle relaxants. Choline derivatives
Used for muscle relaxation during tracheal intubation, endoscopic procedures (bronchial, esophageal, laryngeal, cystoscopic), quick surgeries requiring muscle relaxation (fixing dislocations, repositioning bone fragments), for maintenance of muscle paralysis during surgery (gynaecological, thoracic, abdominal), elimination of tetanus spasms.
For intravenous bolus injection and infusion, or intramuscular administration.
Dithylin-Darnitsa administration is allowed only when artificial ventilation is available.
Adults. The dose is selected by the physician individually, taking into account the body weight, the patient's reaction, the degree of muscle relaxation required, and the route of administration.
For endotracheal intubation, the drug is administered intravenously at a dose of 1 mg/kg body weight. This dose usually causes muscle relaxation after 30-60 seconds lasting from 2 to 6 minutes. Higher doses cause longer muscle relaxation, but doubling the dose does not necessarily result in a doubling of the relaxation time. Extra doses of dithylin, ranging from 50% to 100% of the initial dose, should be administered at intervals of 5 to 10 minutes, and will maintain muscle relaxation during quick surgery under general anaesthesia.