Topical nonsteroidal anti-inflammatory drugs. Ketoprofen
The active substance of the medicine, ketoprofen, belongs to the group of nonsteroidal anti-inflammatory drugs, arylpropionic acid derivatives. Ketoprofen has analgesic and anti-inflammatory effects due to inhibition of cyclooxygenase 1 (COG-1), cyclooxygenase 2 (COG-2) and bradykinin, stabilisation of the lysosomal membranes and inhibition of macrophage migration.
– Muscle and joint pain caused by trauma or injuries.
Three to five cm or more of F-gel should be applied to the skin of the affected area as a thin layer of 3-5 cm 1–2 times per day and gently rubbed in until fully absorbed. The quantity of gel depends on the size of the affected area – 5 cm of gel equals 100 mg of ketoprofen, 10 cm of gel equals 200 mg of ketoprofen. After each use of the medicine, hands should be washed immediately.
F-gel can be combined with other dosage forms of ketoprofen (capsules, tablets, rectal suppositories). The total maximum daily dose of ketoprofen should not exceed 200 mg regardless of the dosage form used.
The treatment duration is determined on an individual basis but should not be more than 10 days.