Levofloxacin, a synthetic antibacterial agent from the fluoroquinolone group, is the S-enantiomer of the racemic mixture of ofloxacin. Mechanism of Action. As an antibiotic from the fluoroquinolone group, levofloxacin acts on the DNA-DNA gyrase complex and topoisomerase IV.
Infectious diseases of mild and moderate severity caused by drug-sensitive microorganisms: acute sinusitis, exacerbation of chronic bronchitis, pneumonia, complicated and uncomplicated urinary tract infections (including pyelonephritis), skin and soft tissue infections, chronic bacterial prostatitis.
The drug should be taken 1 or 2 times per day, regardless of food intake (can be taken both with food and at other times). Swallow without chewing, with a sufficient amount of liquid.
The total dose depends on the infection type and severity. The treatment duration depends on the course of the disease. It is recommended to continue levofloxacin treatment for 48–72 hours after body temperature normalisation or in the absence of pathogens confirmed by microbiological tests.