Nonsteroidal anti-inflammatory and anti-rheumatic drugs
Mefenamic acid is a nonsteroidal anti-inflammatory drug. The anti-inflammatory action mechanism is due to its ability to inhibit the synthesis of inflammatory mediators (prostaglandins, serotonin, kinins, etc.), reduce the activity of lysosomal enzymes involved in the inflammatory response.
Acute viral respiratory infections and influenza.
Mild and moderate pain: muscular, joint, traumatic, dental, headaches of different aetiology, postoperative and postpartum pain.
Primary dysmenorrhea. Dysfunctional menorrhagia, including that caused by intrauterine contraceptives, in the absence of pelvic organ pathology.
Inflammatory diseases of the musculoskeletal system: rheumatoid arthritis, rheumatism, ankylosing spondylitis.
The drug should be administered under the supervision of a physician who determines the dose and duration of treatment. For oral administration. The drug should be taken after meals with milk.
Adults and children aged 12 years and over are prescribed 250–500 mg 3–4 times per day. If indicated and well-tolerated, the daily dose is increased to the maximum of 3000 mg, after the therapeutic effect is reached, the dose is reduced to 1000 mg/day.
For children from 5 to 12 years — 250 mg 3–4 times per day.
The course of treatment for joint diseases can last from 20 days to 2 months or more. In pain syndrome the course of treatment lasts up to 7 days.
The drug is contraindicated for children under 5 years.