The active substance of the medicine, myramistin, is a cationic surfactant with antimicrobial (antiseptic) action. The action is based on direct hydrophobic interaction of the myramistin molecule with the membrane lipids of microorganisms that leads to their fragmentation and destruction.
Surgery, traumatology: topical treatment of infected wounds of different localisation and aetiology; prevention of secondary infections of granulating wounds.
Combustiology: treatment of II and IIIA degree burns; preparation of burn wounds for skin grafting.
Dermatology: strepto-, staphyloderma, tinea corporis, tinea pedis and dermatomycosis of large skin folds (including dyshidrotic forms and forms complicated by pyoderma), tinea unguium (onychomycosis), keratomycosis (including tinea versicolor), candidiasis of the skin and mucosa.
Prevention of infectious wound complications in non-major industrial and household injuries.
Use topically in adults.
Treatment of wounds and burns.
After the standard treatment of wounds and burns, the ointment should be applied directly to the affected surface, then a sterile gauze dressing should be applied, or the ointment applied to the dressing and then to the wound.
Also, drug-impregnated gauze sponges can be used for careful filling of purulent wound cavities after their surgical treatment, or gauze turundas with ointment can be introduced into fistula tracts.
The medicine should be applied once per day for the treatment of purulent wounds and burns in the first phase of the wound healing and once every 1–3 days in the second phase, depending on the wound condition. The dose depends on the wound surface area and the amount of purulent exudate. The treatment duration depends on the dynamics of wound clearing and healing. In deep soft tissue infection, it is possible to use the medicine together with systemic antibiotics; the duration of therapy is determined by the duration of the antibiotic treatment course.
Treatment of dermatological diseases.
Apply a thin film to the affected areas of the skin, or apply ointment to the dressing and then to the lesion 1–2 times per day. Duration of treatment: the medicine should be used until a negative microbiological test result is obtained. In disseminated dermatomycosis, in particular, mycosis caused by Trichophyton rubrum, the ointment can be used for 5–6 weeks in complex therapy with griseofulvin or systemic antifungal medicines. In fungal nail infections, the nail plate should be filed down before treatment.