Novocaine is a local anaesthetic with a moderate activity and a broad range of therapeutic effects. The anaesthetic mechanism is associated with blocking sodium channels, inhibition of potassium ion movement, competition with calcium, reduction of membrane phospholipid layer surface tension, inhibition of redox processes and impulse generation.
Conductive, epidural, and spinal anaesthesia in surgery, urology, ophthalmology, dentistry, otorhinolaryngology, peripheral nerve and nerve plexus block.
The dose of the drug usually depends on the type of anaesthesia, the degree of tissue vascularisation, the required depth and duration of anaesthesia, as well as the individual characteristics of the patient. The lowest effective dose should be administered.
Contraindicated in children.