Class IA antiarrhythmic drugs. Procainamide
The active substance of the drug, procainamide, belongs to class IA antiarrhythmic agents and has a membrane-stabilizing effect. It slows down the inward flow of sodium ions, reducing the rate of depolarization in phase 0.
Heart rhythm disorders: ventricular arrhythmias (extrasystole, tachycardia).
The drug should be used in adults, if necessary, to quickly stop the onset of arrhythmia/control severe arrhythmia, or of oral administration is impossible (due to nausea, vomiting, ineffective absorption of the oral dosage form in the digestive tract, as well as before surgery).
The drug should be diluted with 5% glucose (dextrose) solution and administered intravenously as a slow injection or infusion (at a rate not exceeding 50 mg/minute) under constant pulse, blood pressure, and electrocardiogram (ECG) monitoring.
In cases when, after heart rhythm normalisation, the patient is switched to oral therapy with novocainamide, the interval between the last intravenous administration and the first oral administration should be at least 3-4 hours.