Medications used in functional disorders of the digestive system
Papaverine is an alkaloid contained in opium. Papaverine is a myotropic antispasmodic agent. It lowers the tone, reduces the contractile activity of smooth muscles and therefore has vasodilatory and antispasmodic effects. Papaverine is an inhibitor of the phosphodiesterase enzyme that causes intracellular accumulation of cyclic 3', 5'-adenosine monophosphate (cAMP). Accumulation of cAMP leads to impaired contractility of the smooth muscles and their relaxation in spastic conditions. The effect of the drug on the central nervous system is poorly expressed, only in high doses does it show some sedative effect.
Spasms of smooth muscles of abdominal organs (pylorospasm, irritable bowel syndrome, cholecystitis, attacks of gallstone disease);
spasms of the urinary tract, renal colic;
spasm of cerebral vessels;
spasms of peripheral vessels (endarteritis).
Safety and efficacy of the drug during pregnancy or lactation have not been established. Breast-feeding should be discontinued during the treatment with the drug.
The ability to affect the rate of response when driving vehicles or operating other mechanisms.
During the treatment with the drug you should refrain from driving vehicles or operating other complex mechanisms.