Systemic antimicrobial agents. Long-acting sulfanilamides
Antimicrobial bacteriostatic agent, long-acting sulfanilamide. The mechanism of action is associated with competitive antagonism of para-aminobenzoic acid, inhibition of dihydropteroate synthase, interruption of tetrahydrofolate acid synthesis needed for the synthesis of purines and pyrimidines.
Infectious diseases caused by microflora susceptible to the drug: tosillitis, bronchitis, pneumonia, sinusitis, otitis, dysentery, inflammatory biliary and urinary tract diseases, gonorrhea, erysipelas, pyoderma, meningitis, wound infections, trachoma, toxoplasmosis, shigellosis, resistant forms of malaria (in combination with antimalarial drugs).
The drug is prescribed for oral administration once per day with an interval of 24 hours between doses.
For adults1–2 g of sulfadimethoxine (2–4 tablets) is prescribed on day 1, and 500 mg–1 g of sulfadimethoxine (1–2 tablets) in the following days.