Torasemide acts as saluretic; its effect is associated with inhibiting renal absorption of sodium and chloride ions in the ascending limb of the loop of Henle. In humans, the diuretic effect quickly reaches its maximum in the first 2–3 hours after intravenous and oral administration, respectively, and remains stable for almost 12 hours.
For 5 mg dose:
— essential hypertension.
For 5 mg and 10 mg doses:
— treatment and preventing recurrence of oedemas and/or effusions caused by heart failure.
For 5 mg dose.
Essential hypertension. Treatment should be initiated with ½ 5 mg tablet of Torasemide-Darnitsa per day which is equivalent to 2.5 mg of torasemide. The blood pressure decrease occurs gradually, already during the first week of the treatment, and reaches the maximum no later than 12 weeks. If the blood pressure normalisation does not occur after 12 weeks of treatment with 2.5 mg of torasemide daily, the daily dose can be increased to 5 mg of torasemide. In initially high blood pressure and in limited renal function, an additional decrease in blood pressure after increasing the dose can be expected.