Antiseptics and disinfectants
The action of myramistin is based on the direct hydrophobic interaction of the molecule with the membrane lipids of microorganisms that leads to their fragmentation and destruction. A part of the myramistin molecule, by penetrating into the hydrophobic region of the membrane, destroys the supramembrane layer, loosens the membrane, increases its permeability for high-molecular-weight substances, changes the enzyme activity of the microbial cells, inhibiting the enzyme systems, which leads to suppressing the processes vital for microorganisms and their cytolysis.
Surgery, traumatology: topical treatment of infected wounds of different localisation and aetiology; prevention of secondary infections of granulating wounds.
Combustiology: treatment of II and IIIA degree burns; preparation of burn wounds for skin grafting.
Obstetrics and gynaecology: prevention and treatment of suppuration of postpartum wounds, postpartum infections, perineal and vaginal wounds; inflammatory diseases of the external genitalia and vagina (vulvovaginitis).
Dermatology: complex treatment of candidiasis of the skin and mucosa, tinea pedis and mycosis of large skin folds.
Venereology: individual prevention of sexually transmitted diseases (syphilis, gonorrhoea, genital herpes).
Otorhinolaryngology: complex treatment of acute and chronic otitis, sinusitis, tonsillitis.
Dentistry: treatment of periodontitis, stomatitis; hygienic treatment of dentures; prevention of microbial complications after surgery on the oral mucosa.
Apply topically in adults.
Surgery, traumatology, combustiology. For prevention and treatment, irrigate the surface of wounds and burns with Myramistin®, perform a loose tamponade of the wound and fistula tracts, then fix gauze sponges soaked in antiseptic. Repeat the treatment procedure 2–3 times a day for 3–5 days. The effective method is active drainage of wounds and cavities with a daily consumption of about 1 liter of the drug.
As there is insufficient experience of using myramistin solution in children, it should not be used in paediatric practice.