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Dvatse 100

N-acetyl-L-cysteine (AC) has a marked mucolytic effect on mucous and mucopurulent secretions due to depolymerization of mucoprotein complexes and nucleic acids, which give viscosity to hyaline and purulent components of sputum and other secretions. Additional properties: reduction of induced mucocyte hyperplasia, increase of surfactant production due to stimulation of type II pneumocytes, stimulation of activity of mucociliary apparatus, which furthers the improvement of mucociliary clearance. AC also has a direct antioxidant effect due to the presence of a nucleophilic free thiol group (SH), which can directly interact with the electrophilic groups of oxidative radicals. Of particular interest is the fact that AC prevents the inactivation of α-1-antitrypsin (an enzyme that inhibits elastase) by hydrochloric acid (HOCl) - a strong oxidant produced by myeloperoxidase of active phagocytes.

Treatment of acute and chronic diseases of the bronchopulmonary system accompanied with increased sputum production.

Adults

400 to 600 mg a day divided into 1 to 3 doses.

Children

2 to 6 years: 200 to 400 mg a day divided into 1 to 3 doses;

6 to 12 years: 400–600 mg a day divided into 1 to 3 doses;

aged 12 years and above – doses as for adults.

It is recommended to take the medicinal product after meals.

Dissolve granules in 1/3 cup of water and drink the solution without delay, immediately after preparation.

When dissolving acetylcysteine, it is necessary to use glassware, avoid contact with metal and rubber surfaces.

Additional fluid intake enhances the mucolytic effect of the medicinal product.

The duration of treatment is determined by the doctor individually, depending on the nature of the disease. For acute uncomplicated diseases, acetylcysteine should be used for 4 to 5 days.

Children.

Use in children aged 2 years and above.

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